APP anticorps (C-Term)
Aperçu rapide pour APP anticorps (C-Term) (ABIN2787850)
Antigène
Voir toutes APP AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- C-Term
-
Séquence
- LVMLKKKQYT SIHHGVVEVD AAVTPEERHL SKMQQNGYEN PTYKFFEQMQ
-
Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
-
Attributs du produit
- This is a rabbit polyclonal antibody against App. It was validated on Western Blot.
-
Purification
- Affinity Purified
-
Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human App
-
-
-
-
Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
-
Commentaires
-
Antigen size: 751 AA
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- Lot specific
-
Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
-
Stock
- -20 °C
-
Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- APP (Amyloid beta (A4) Precursor Protein (APP))
-
Autre désignation
- App
-
Sujet
-
App functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. It is involved in cell mobility and transcription regulation through protein-protein interactions.
Alias Symbols: Abeta, Abpp, Adap, Ag, betaApp, Cvap, E030013M08Rik
Protein Interaction Partner: Ranbp9, Cpeb1, Bace1, Snca, Prnp, Gga1, Stub1, Ubc, Kif1a, Mme, Mapk8ip2, Mapk8ip1, Dab1,
Protein Size: 751 -
Poids moléculaire
- 83 kDa
-
ID gène
- 11820
-
NCBI Accession
- NM_001198824, NP_001185753
-
UniProt
- P12023
-
Pathways
- Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour
Antigène
-